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Article

Autoimmune alterations induced by the New Zealand Black Lbw2 locus in BWF1 mice.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2005

Haraldsson Maria K, dela Paz Nathanial G, Kuan Jason G, Gilkeson Gary S, Theofilopoulos Argyrios N, Kono Dwight H

Abstract excerpt

The New Zealand Black (NZB) Lbw2 locus (lupus NZB x New Zealand White (NZW) 2 locus) was previously linked to mortality and glomerulonephritis, but not to IgG autoantibodies, suggesting that it played a role in a later disease stage. To define its contribution, (NZB x NZW)F1 hybrids (BWF1) containing two, one, or no copies of this locus were generated. Lack of the NZB Lbw2 indeed reduced mortality and...

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Identifiers

PMID: 15814738
DOI: 10.4049/jimmunol.174.8.5065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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