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Article

Differential role of three major New Zealand Black-derived loci linked with Yaa-induced murine lupus nephritis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2005

Kikuchi Shuichi, Fossati-Jimack Liliane, Moll Thomas, Amano Hirofumi, Amano Eri, Ida Akinori, Ibnou-Zekri Nabila, Laporte Catherine, Santiago-Raber Marie-Laure, Rozzo Stephen J, Kotzin Brian L, Izui Shozo

Abstract excerpt

By assessing the development of Y-linked autoimmune acceleration (Yaa) gene-induced systemic lupus erythematosus in C57BL/6 (B6) x (New Zealand Black (NZB) x B6.Yaa)F(1) backcross male mice, we mapped three major susceptibility loci derived from the NZB strain. These three quantitative trait loci (QTL) on NZB chromosomes 1, 7, and 13 differentially regulated three different autoimmune traits: anti-nuclear...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15634937
DOI: 10.4049/jimmunol.174.2.1111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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