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Article

New loci from New Zealand Black and New Zealand White mice on chromosomes 4 and 12 contribute to lupus-like disease in the context of BALB/c.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2004

Rigby Robert J, Rozzo Stephen J, Boyle Joseph J, Lewis Margarita, Kotzin Brian L, Vyse Timothy J

Abstract excerpt

New Zealand Black (NZB) and New Zealand White (NZW) mice are genetically predisposed to a lupus-like autoimmune syndrome. To further define the loci linked to disease traits in NZB and NZW mice in the context of the BALB/c genetic background, linkage analyses were conducted in two crosses: (NZW x BALB/c.H2(z))F(1) x NZB and (NZB x BALB/c)F(2). Novel loci linked to autoantibody production and glomerulonephritis,...

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Identifiers

PMID: 15034079
DOI: 10.4049/jimmunol.172.7.4609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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