Article
Lupus susceptibility loci in New Zealand mice.
Proceedings of the National Academy of Sciences of the United States of America - 11 Oct 1994
Kono D H, Burlingame R W, Owens D G, Kuramochi A, Balderas R S, Balomenos D, Theofilopoulos A N
Abstract excerpt
Susceptibility to systemic lupus erythematosus has been unequivocally established to be an inherited trait, but the exact genes and how they confer susceptibility remain largely unknown. In this study of (NZB x NZW)F2 intercross mice, we used linkage analysis of markers covering > 90% of the auto...
Topics
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Female
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Genome
- Lupus Erythematosus, Systemic
- Mice
- Mice, Inbred Strains
- New Zealand
- Splenomegaly