Article
New Zealand mixed mice: a genetic systemic lupus erythematosus model for assessing environmental effects.
Environmental health perspectives - 1 Oct 1999
Rudofsky U H, Lawrence D A
Abstract excerpt
Systemic lupus erythematosus (SLE) is a multiphenotypic autoimmune disease. The hallmark of SLE is the production of anti-double-stranded DNA autoantibodies and the deposition of immune complexes in target tissues such as the kidney, skin, and brain. Additional phenotypic traits are the presence of arthritis, anemia, central nervous system involvement, and a variety of autoantibodies. Females of childbearing age...
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