Article
Analysis and exploration of the use of rule-based algorithms and consensus methods for the inferral of haplotypes.
Genetics - 1 Oct 2003
Orzack Steven Hecht, Gusfield Daniel, Olson Jeffrey, Nesbitt Steven, Subrahmanyan Lakshman, Stanton Vincent P
Abstract excerpt
The difficulty of experimental determination of haplotypes from phase-unknown genotypes has stimulated the development of nonexperimental inferral methods. One well-known approach for a group of unrelated individuals involves using the trivially deducible haplotypes (those found in individuals with zero or one heterozygous sites) and a set of rules to infer the haplotypes underlying ambiguous genotypes (those...
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