Article
Haplotype inference for present-absent genotype data using previously identified haplotypes and haplotype patterns.
Bioinformatics (Oxford, England) - 15 Sept 2007
Yoo Yun Joo, Tang Jianming, Kaslow Richard A, Zhang Kui
Abstract excerpt
MOTIVATION: Killer immunoglobulin-like receptor (KIR) genes vary considerably in their presence or absence on a specific regional haplotype. Because presence or absence of these genes is largely detected using locus-specific genotyping technology, the distinction between homozygosity and hemizygosity is often ambiguous. The performance of methods for haplotype inference (e.g. PL-EM, PHASE) for KIR genes may be...
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