Identification of probable genotyping errors by consideration of haplotypes.

doi:10.1038/sj.ejhg.5201565

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Article

Identification of probable genotyping errors by consideration of haplotypes.

European journal of human genetics : EJHG - 1 Apr 2006

Becker Tim, Valentonyte Ruta, Croucher Peter J P, Strauch Konstantin, Schreiber Stefan, Hampe Jochen, Knapp Michael

Abstract excerpt

Undetected genotyping errors pose a problem in genetic epidemiological studies, as they may invalidate statistical analysis or reduce its power. Haplotype analysis requires an improved standard of the data, because a haplotype can be inferred correctly only if the genotypes of all its markers are...

Topics

Computer Simulation
Gene Frequency
Genetic Markers
Genotype
Haplotypes
Humans
Models, Genetic
Predictive Value of Tests
Research Design

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