Article
Identification of probable genotyping errors by consideration of haplotypes.
European journal of human genetics : EJHG - 1 Apr 2006
Becker Tim, Valentonyte Ruta, Croucher Peter J P, Strauch Konstantin, Schreiber Stefan, Hampe Jochen, Knapp Michael
Abstract excerpt
Undetected genotyping errors pose a problem in genetic epidemiological studies, as they may invalidate statistical analysis or reduce its power. Haplotype analysis requires an improved standard of the data, because a haplotype can be inferred correctly only if the genotypes of all its markers are correct. Here, we present a method that identifies probable genotyping errors in trio samples with the help of the...
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