The impact of genotyping error on haplotype reconstruction and frequency estimation.

doi:10.1038/sj.ejhg.5200855

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Article

The impact of genotyping error on haplotype reconstruction and frequency estimation.

European journal of human genetics : EJHG - 1 Oct 2002

Kirk Katherine M, Cardon Lon R

Abstract excerpt

The choice of genotyping families vs unrelated individuals is a critical factor in any large-scale linkage disequilibrium (LD) study. The use of unrelated individuals for such studies is promising, but in contrast to family designs, unrelated samples do not facilitate detection of genotyping erro...

Topics

Diagnostic Errors
Gene Frequency
Genotype
Haplotypes
Linkage Disequilibrium
Research Design

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