Article
Comparison of the accuracy of methods of computational haplotype inference using a large empirical dataset.
BMC genetics - 3 Aug 2004
Adkins Ronald M
Abstract excerpt
BACKGROUND: Analyses of genetic data at the level of haplotypes provide increased accuracy and power to infer genotype-phenotype correlations and evolutionary history of a locus. However, empirical determination of haplotypes is expensive and laborious. Therefore, several methods of inferring hap...
Topics
- Algorithms
- Bayes Theorem
- Gene Frequency
- Genetic Linkage
- Haplotypes
- Human Growth Hormone
- Humans
- Mathematical Computing
- Models, Genetic
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic
- Software