Article
Effectiveness of computational methods in haplotype prediction.
Human genetics - 1 Feb 2002
Xu Chun-Fang, Lewis Karen, Cantone Kathryn L, Khan Parveen, Donnelly Christine, White Nicola, Crocker Nikki, Boyd Pete R, Zaykin Dmitri V, Purvis Ian J
Abstract excerpt
Haplotype analysis has been used for narrowing down the location of disease-susceptibility genes and for investigating many population processes. Computational algorithms have been developed to estimate haplotype frequencies and to predict haplotype phases from genotype data for unrelated individ...
Topics
- Arylamine N-Acetyltransferase
- Computational Biology
- DNA
- DNA Primers
- Gene Frequency
- Haplotypes
- Humans
- Linkage Disequilibrium
- Male
- North Carolina
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide