Article
Effectiveness of computational methods in haplotype prediction.
Human genetics - 1 Feb 2002
Xu Chun-Fang, Lewis Karen, Cantone Kathryn L, Khan Parveen, Donnelly Christine, White Nicola, Crocker Nikki, Boyd Pete R, Zaykin Dmitri V, Purvis Ian J
Abstract excerpt
Haplotype analysis has been used for narrowing down the location of disease-susceptibility genes and for investigating many population processes. Computational algorithms have been developed to estimate haplotype frequencies and to predict haplotype phases from genotype data for unrelated individuals. However, the accuracy of such computational methods needs to be evaluated before their applications can be...
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