Article
Evaluation of consensus strategies for haplotype phasing.
Briefings in bioinformatics - 20 Jul 2021
Al Bkhetan Ziad, Chana Gursharan, Ramamohanarao Kotagiri, Verspoor Karin, Goudey Benjamin
Abstract excerpt
Haplotype phasing is a critical step for many genetic applications but incorrect estimates of phase can negatively impact downstream analyses. One proposed strategy to improve phasing accuracy is to combine multiple independent phasing estimates to overcome the limitations of any individual estimate. However, such a strategy is yet to be thoroughly explored. This study provides a comprehensive evaluation of...
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