Article
Notes from the SNP vs. haplotype front.
Pharmacogenomics - 1 Feb 2001
Judson R, Stephens J C
Abstract excerpt
Single nucleotide polymorphisms (SNPs) and haplotypes are commonly used genetic markers in clinical studies. We provide some broad guidelines for deciding which of the two is most appropriate in particular circumstances. Molecular haplotyping techniques are also briefly reviewed and contrasted with electronic approaches.
Topics
- Genetic Markers
- Genetic Variation
- Genome, Human
- Haplotypes
- Heteroduplex Analysis
- Humans
- Linkage Disequilibrium
- Pharmacogenetics
- Polymorphism, Single Nucleotide
- Sequence Analysis, DNA