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Article

Simple estimates of haplotype relative risks in case-control data.

Genetic epidemiology - 1 Sept 2006

French Benjamin, Lumley Thomas, Monks Stephanie A, Rice Kenneth M, Hindorff Lucia A, Reiner Alexander P, Psaty Bruce M

Abstract excerpt

Methods of varying complexity have been proposed to efficiently estimate haplotype relative risks in case-control data. Our goal was to compare methods that estimate associations between disease conditions and common haplotypes in large case-control studies such that haplotype imputation is done once as a simple data-processing step. We performed a simulation study based on haplotype frequencies for two...

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PMID: 16755519
DOI: 10.1002/gepi.20161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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