Article
Ability of adenovirus 5 E1A proteins to suppress differentiation of BC3H1 myoblasts correlates with their binding to a 300 kDa cellular protein.
Molecular biology of the cell - 1 Oct 1992
Mymryk J S, Lee R W, Bayley S T
Abstract excerpt
We have used deletion mutants to define the regions in Ad5 E1A proteins necessary to suppress differentiation of mouse BC3H1 myoblasts. We examined the differentiation of cells infected at a low multiplicity with viruses containing the E1A deletions and constructed so as to produce only the small...
Topics
- Adenovirus E1A Proteins
- Animals
- Cell Differentiation
- Cell Line
- Chromosome Mapping
- Mice
- Molecular Weight
- Muscles
- Mutation
- Protein Binding
- Transcription Factors
- Transfection