Article
Induction of DNA synthesis and apoptosis in cardiac myocytes by E1A oncoprotein.
The Journal of cell biology - 1 Apr 1996
Liu Y, Kitsis R N
Abstract excerpt
Beginning during the second half of gestation, increasing numbers of cardiac myocytes withdraw from the cell cycle such that DNA synthesis is no longer detectable in these cells by neonatal day 17 in vivo. The mechanisms that exclude these and other terminally differentiated cells from the cell d...
Topics
- Adenovirus E1A Proteins
- Adenoviruses, Human
- Animals
- Apoptosis
- Cells, Cultured
- DNA
- E1A-Associated p300 Protein
- Fetal Heart
- Humans
- Mutation
- Myocardium
- Nuclear Proteins
- Phosphoproteins
- Protein Binding
- Proteins
- Rats
- Rats, Sprague-Dawley
- Retinoblastoma Protein