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Article

Induction of DNA synthesis and apoptosis in cardiac myocytes by E1A oncoprotein.

The Journal of cell biology - 1 Apr 1996

Liu Y, Kitsis R N

Abstract excerpt

Beginning during the second half of gestation, increasing numbers of cardiac myocytes withdraw from the cell cycle such that DNA synthesis is no longer detectable in these cells by neonatal day 17 in vivo. The mechanisms that exclude these and other terminally differentiated cells from the cell division cycle are poorly understood. To begin to explore the molecular basis of the barrier to G1/S progression in...

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Identifiers

PMID: 8609165
DOI: 10.1083/jcb.133.2.325
PMCID: PMC2120791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Induction of DNA synthesis and apoptosis in cardiac myocytes by E1A oncoprotein.PMID 8609165Read ↗

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Transforming growth factor beta1 receptor II is downregulated by E1A in adenovirus-infected cells.Semantic proximity Read ↗

The adenovirus E1A domains required for induction of DNA rereplication in G2/M arrested cells coincide with those required for apoptosis.Semantic proximity Read ↗

bcl-2 overexpression promotes myocyte proliferation.Semantic proximity Read ↗

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Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis.Semantic proximity Read ↗

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