Article
Multiple pathways for gene activation in rodent cells by the smaller adenovirus 5 E1A protein and their relevance to growth and transformation.
The Journal of general virology - 1 Oct 1993
Mymryk J S, Bayley S T
Abstract excerpt
By immunoprecipitating protein products from virus-infected baby rat kidney (BRK) cells with specific antibodies, we found that the smaller, 243 residue (243R) E1A protein of human adenovirus 5 (Ad5) activated expression of the virus genes for E1B 55K, E2A 72K, E3 19K, hexon, fibre and penton bas...
Topics
- Adenovirus E1A Proteins
- Adenoviruses, Human
- Animals
- Cells, Cultured
- Chromosome Mapping
- Gene Deletion
- Gene Expression Regulation, Viral
- Mutation
- Protein Binding
- Rats
- Rats, Wistar
- Transcriptional Activation
- Transformation, Genetic