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Article

Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth

1 Jan 1993

Abstract excerpt

Adenovirus early region 1A (E1A) oncogene-encoded sequences essential for transformation- and cell growth-regulating activities are localized at the N terminus and in regions of highly conserved amino acid sequence designated conserved regions 1 and 2. These regions interact to form the binding sites for two classes of cellular proteins: those, such as the retinoblastoma gene product, whose association with the...

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PMID: 8416379
DOI: 10.1128/jvi.67.1.476-488.1993

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Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growthPMID 8416379Read ↗

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