Article
Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization.
Genes & development - 1 Apr 1990
Brennan T J, Olson E N
Abstract excerpt
Myogenin is a member of a family of muscle-specific factors that can activate the muscle differentiation program in nonmyogenin cells. Using antibodies directed against unique domains of myogenin, we show in the present study that myogenin resides in the nucleus of differentiated muscle cells. Myogenin translated in vitro does not exhibit detectable DNA binding activity; however, when dimerized with the...
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