Article
Relationship of DNA double-strand breaks to synapsis in Drosophila.
Journal of cell science - 1 Aug 2003
Jang Janet K, Sherizen Dalia E, Bhagat Rajal, Manheim Elizabeth A, McKim Kim S
Abstract excerpt
The relationship between synaptonemal complex formation (synapsis) and double-strand break formation (recombination initiation) differs between organisms. Although double-strand break creation is required for normal synapsis in Saccharomyces cerevisiae and the mouse, it is not necessary for synapsis in Drosophila and Caenorhabditis elegans. To investigate the timing of and requirements for double-strand break...
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