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Article

Zip2, a meiosis-specific protein required for the initiation of chromosome synapsis.

Cell - 1 May 1998

Chua P R, Roeder G S

Abstract excerpt

We describe the identification and characterization of the Saccharomyces cerevisiae ZIP2 gene, which encodes a novel meiosis-specific protein essential for synaptonemal complex formation. In the zip2 mutant, chromosomes are homologously paired but not synapsed. The Zip2 protein localizes to discrete foci on meiotic chromosomes; these foci correspond to sites of convergence between paired homologs that are...

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PMID: 9590170
DOI: 10.1016/s0092-8674(00)81164-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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