Article
The Hop2 protein has a direct role in promoting interhomolog interactions during mouse meiosis.
Developmental cell - 1 Dec 2003
Petukhova Galina V, Romanienko Peter J, Camerini-Otero R Daniel
Abstract excerpt
The S. cerevisiae Hop2 protein and its fission yeast homolog Meu13 are required for proper homologous chromosome pairing and recombination during meiosis. The mechanism of this requirement is, however, not understood. The previous studies in Saccharomyces suggested that Hop2 is a guardian of meiotic chromosome synapsis with the ability to prevent or resolve deleterious associations between nonhomologous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
