Article
Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis.
Cell - 7 Aug 1998
Dernburg A F, McDonald K, Moulder G, Barstead R, Dresser M, Villeneuve A M
Abstract excerpt
Chromosome segregation at meiosis I depends on pairing and crossing-over between homologs. In most eukaryotes, pairing culminates with formation of the proteinaceous synaptonemal complex (SC). In budding yeast, recombination initiates through double-strand DNA breaks (DSBs) and is thought to be e...
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