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Article

Synaptonemal Complex Components Are Required for Meiotic Checkpoint Function in Caenorhabditis elegans.

Genetics - 1 Nov 2016

Bohr Tisha, Ashley Guinevere, Eggleston Evan, Firestone Kyra, Bhalla Needhi

Abstract excerpt

Synapsis involves the assembly of a proteinaceous structure, the synaptonemal complex (SC), between paired homologous chromosomes, and is essential for proper meiotic chromosome segregation. In Caenorhabditis elegans, the synapsis checkpoint selectively removes nuclei with unsynapsed chromosomes by inducing apoptosis. This checkpoint depends on pairing centers (PCs), cis-acting sites that promote pairing and...

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Identifiers

PMID: 27605049
DOI: 10.1534/genetics.116.191494
PMCID: PMC5105873

Genes

SYP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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