Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombination.

Developmental cell - 1 Sept 2003

Colaiácovo Mónica P, MacQueen Amy J, Martinez-Perez Enrique, McDonald Kent, Adamo Adele, La Volpe Adriana, Villeneuve Anne M

Abstract excerpt

Here we probe the relationships between assembly of the synaptonemal complex (SC) and progression of recombination between homologous chromosomes during Caenorhabditis elegans meiosis. We identify SYP-2 as a structural component of the SC central region and show that central region assembly depends on proper morphogenesis of chromosome axes. We find that the SC central region is dispensable for initiation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Pairing
Share to Crossing Over, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endodeoxyribonucleases

Share to Esterases

Share to Indoles

Share to Meiosis

Share to Rad51 Recombinase

Share to Synaptonemal Complex

Source

Identifiers

PMID: 12967565
DOI: 10.1016/s1534-5807(03)00232-6

Genes

SYP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombination.PMID 12967565Read ↗

CRA-1 uncovers a double-strand break-dependent pathway promoting the assembly of central region proteins on chromosome axes during C. elegans meiosis.Semantic proximity Read ↗

SYCE2 is required for synaptonemal complex assembly, double strand break repair, and homologous recombination.Semantic proximity Read ↗

Synaptonemal complex proteins direct and constrain the localization of crossover-promoting proteins during <i>Caenorhabditis elegans</i> meiosisSemantic proximity Read ↗

HTP-1 coordinates synaptonemal complex assembly with homolog alignment during meiosis in C. elegans.Semantic proximity Read ↗

Identification of novel synaptonemal complex components in C. elegans.Semantic proximity Read ↗

Meiotic recombination modulates the structure and dynamics of the synaptonemal complex during C. elegans meiosis.Semantic proximity Read ↗

SYP-3 restricts synaptonemal complex assembly to bridge paired chromosome axes during meiosis in Caenorhabditis elegans.Semantic proximity Read ↗

Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis.Semantic proximity Read ↗

Synapsis-defective mutants reveal a correlation between chromosome conformation and the mode of double-strand break repair during Caenorhabditis elegans meiosis.Semantic proximity Read ↗

A component of C. elegans meiotic chromosome axes at the interface of homolog alignment, synapsis, nuclear reorganization, and recombination.Semantic proximity Read ↗

Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans.Semantic proximity Read ↗

Distinct cellular and reproductive consequences of meiotic chromosome synapsis defects in syce2 and sycp1 mutant zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.