Article
Temporal analysis of meiotic DNA double-strand break formation and repair in Drosophila females.
PLoS genetics - 24 Nov 2006
Mehrotra S, McKim K S
Abstract excerpt
Using an antibody against the phosphorylated form of His2Av (gamma-His2Av), we have described the time course for the series of events leading from the formation of a double-strand break (DSB) to a crossover in Drosophila female meiotic prophase. MEI-P22 is required for DSB formation and localizes to chromosomes prior to gamma-His2Av foci. Drosophila females, however, are among the group of organisms where...
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