Article
Lack of association between interleukin-1alpha polymorphism and Alzheimer disease or vascular dementia.
Alzheimer disease and associated disorders - 1 Jan 2000
Kuo Yu-Min, Liao Pao-Chi, Lin Chingju, Wu Chih-Wei, Huang Hsueh-Meei, Lin Chih-Chien, Chuo Liang-Jen
Abstract excerpt
Recently, a C/T polymorphism in the promoter region of the interleukin 1-alpha (IL-1alpha) gene (position -889) was reported to be associated with Alzheimer disease. In this study, the polymorphism of IL-1alpha was examined in patients with Alzheimer disease, vascular dementia, and nondemented controls in a Chinese population in Taiwan. No difference was found in the IL-1alpha T allele frequency among the three...
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