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Association between the interleukin-1alpha gene and Alzheimer's disease: a meta-analysis.

Neurobiology of aging - 1 Jan 2000

Rainero I, Bo M, Ferrero M, Valfrè W, Vaula G, Pinessi L

Abstract excerpt

Inflammatory processes are involved in the pathogenesis of Alzheimer's disease (AD). Several studies have addressed the effects of interleukin-1 (IL-1) genes polymorphisms on the risk of developing AD. The results are not in full agreement on whether these polymorphisms are associated with the disease. To clarify this issue, we performed a meta-analysis of all the association studies between IL-1 genes and AD....

Topics

Aged
Alzheimer Disease
Comorbidity
Female
Genetic Predisposition to Disease
Humans
Interleukin-1
Male
Middle Aged
Mutation
Phenotype
Risk Assessment

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Identifiers

PMID: 15465625
DOI: 10.1016/j.neurobiolaging.2004.02.011

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