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Article

Association between tumor necrosis factor-alpha promoter polymorphism and Alzheimer's disease.

Neurology - 27 Jan 2004

Ma Suk Ling, Tang Nelson L S, Lam Linda C W, Chiu Helen F K

Abstract excerpt

Tumor necrosis factor-alpha (TNFalpha) gene polymorphisms have been reported to be associated with Alzheimer's disease (AD) in Caucasian populations. Three TNFalpha polymorphisms (-857, -863, and -1,031) were studied in a Chinese population. A high-risk TNFalpha haplotype (-1,031C-863C-857C) with an odds ratio of 2.54 (95% CI 1.37 to 4.79) for AD was identified. No interaction effect of APOE and TNFalpha...

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Source

Identifiers

PMID: 14745077
DOI: 10.1212/01.wnl.0000103288.49441.e4

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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