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Meta-analysis of the association between the interleukin-1A -889C/T polymorphism and Alzheimer's disease.

Journal of neuroscience research - 1 Sept 2012

Hua Ye, Zhao Hui, Kong Yuenan, Lu Xiaojie

Abstract excerpt

No clear consensus has been reached on the Interleukin-1A (IL-1A) -889C/T polymorphism and Alzheimer's disease (AD) risk. In this meta-analysis, 27 case-control studies were assessed to evaluate the possible association. Overall, positive associations of the IL-1A -889C/T polymorphism with AD risk were found in allele comparison T vs. C (OR = 1.09, 95% CI = 1.01-1.18), recessive model TT vs. CT + CC (OR = 1.21,...

Topics

Age of Onset
Alzheimer Disease
Asian People
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-1alpha
Polymorphism, Single Nucleotide
White People

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22513697
DOI: 10.1002/jnr.23062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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