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Genetic analysis of interleukin-1A C(-889)T polymorphism with Alzheimer disease.

Cellular and molecular neurobiology - 1 Feb 2009

Hu Ji-Liang, Li Gang, Zhou De-Xiang, Zou Yu-Xi, Zhu Zhi-Shan, Xu Ru-Xiang, Jiang Xiao-Dan, Zeng Yan-Jun

Abstract excerpt

Neuroinflammation has been implicated in the etiology of Alzheimer's disease (AD). Many studies have suggested that C(-889) T promoter polymorphism in one of the proinflammatory cytokine interleukin-1 (IL-1) encoding gene IL-1A may be associated with AD pathogenesis. To determine whether the polymorphism contributes to the risk for late-onset AD (LOAD) in Chinese, we carried out our investigation in 344 sporadic...

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PMID: 18709454
DOI: 10.1007/s10571-008-9299-5

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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