Article
Interleukin-1alpha -889 C/T polymorphism in Turkish patients with late-onset Alzheimer's disease.
Dementia and geriatric cognitive disorders - 1 Jan 2009
Dursun Erdinç, Gezen-Ak Duygu, Ertan Turan, Bilgiç Başar, Gürvit Hakan, Emre Murat, Eker Engin, Engin Funda, Uysal Omer, Yilmazer Selma
Abstract excerpt
BACKGROUND/AIMS: The polymorphism (rs1800587) in the 5'-flanking regulatory region at -889 of the interleukin-1alpha gene has been shown to be associated with inflammatory diseases and Alzheimer's disease (AD). The aim of the current study is to determine whether there is an association between the promoter region polymorphism of the interleukin-1alpha gene and late-onset AD in a cohort of Turkish patients....
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