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Article

ATP-dependent roX RNA remodeling by the helicase maleless enables specific association of MSL proteins.

Molecular cell - 25 Jul 2013

Maenner Sylvain, Müller Marisa, Fröhlich Jonathan, Langer Diana, Becker Peter B

Abstract excerpt

Dosage compensation in Drosophila involves a global activation of genes on the male X chromosome. The activating complex (MSL-DCC) consists of male-specific-lethal (MSL) proteins and two long, noncoding roX RNAs. The roX RNAs are essential for X-chromosomal targeting, but their contributions to MSL-DCC structure and function are enigmatic. Conceivably, the RNA helicase MLE, itself an MSL subunit, is actively...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23870143
DOI: 10.1016/j.molcel.2013.06.011

Genes

DCC
MSL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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