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Article

Drosophila MSL complex globally acetylates H4K16 on the male X chromosome for dosage compensation.

Nature structural & molecular biology - 1 Aug 2009

Gelbart Marnie E, Larschan Erica, Peng Shouyong, Park Peter J, Kuroda Mitzi I

Abstract excerpt

The Drosophila melanogaster male-specific lethal (MSL) complex binds the single male X chromosome to upregulate gene expression to equal that from the two female X chromosomes. However, it has been puzzling that approximately 25% of transcribed genes on the X chromosome do not stably recruit MSL...

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Share to Acetylation
Share to Chromatin Immunoprecipitation
Share to Dosage Compensation, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19648925
DOI: 10.1038/nsmb.1644
PMCID: PMC2722042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19648925-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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