Article
Allele and genotype frequencies of CYP2B6 and CYP3A5 in the Japanese population.
European journal of clinical pharmacology - 1 Sept 2002
Hiratsuka Masahiro, Takekuma Yoh, Endo Naomi, Narahara Kaori, Hamdy Samar Ismail, Kishikawa Yukinaga, Matsuura Masaki, Agatsuma Yasuyuki, Inoue Tomoko, Mizugaki Michinao
Abstract excerpt
OBJECTIVE: The goal of this study was to determine the frequencies of allelic variants of CYP2B6and CYP3A5 in the Japanese population. METHODS: Genotyping of CYP2B6 (*2, *3, *4, *5, *6, and *7) and CYP3A5 ( *2, *3, *4, *5, and *6) was carried out in 265 unrelated Japanese subjects by polymerase chain reaction (PCR), restriction fragment length polymorphism and allele-specific, real-time PCR assays. RESULTS:...
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