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Article

Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups.

Pharmacogenetics - 1 Aug 2003

Lee Su-Jun, Usmani Khawja A, Chanas Brian, Ghanayem Burhan, Xi Tina, Hodgson Ernest, Mohrenweiser Harvey W, Goldstein Joyce A

Abstract excerpt

OBJECTIVES: Genetic polymorphisms of cytochromes P450 (CYPs) are a principal reason for inter-individual variations in the metabolism of therapeutic drugs and environmental chemicals in humans. The present study identifies 34 single nucleotide polymorphisms (SNPs) of CYP3A5 including 27 previously unidentified SNPs by direct sequencing of the exons, intron-exon junctions and 5'-upstream region of CYP3A5 from 92...

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PMID: 12893984
DOI: 10.1097/00008571-200308000-00004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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