Article
Frequencies of CYP3A5 genotypes and haplotypes in a Korean population.
Journal of clinical pharmacy and therapeutics - 1 Feb 2008
Park S Y, Kang Y S, Jeong M S, Yoon H K, Han K O
Abstract excerpt
BACKGROUND AND OBJECTIVE: CYP3A, the drug-metabolizing enzyme is an important factor in the pharmacokinetics of many drugs. Polymorphism of the CYP3A5 gene is known to influence the functionality of the CYP3A5 enzymes. The full extent of CYP3A5 genetic polymorphism was analysed in a Korean population. METHODS: Specific polymerase chain reaction-restriction fragment length polymorphism tests for CYP 3AP1 through...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
