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Article

Novel detection assay by PCR-RFLP and frequency of the CYP3A5 SNPs, CYP3A53 and 6, in a Japanese population.

Pharmacogenetics - 1 Jun 2002

Fukuen Shuichi, Fukuda Tsuyoshi, Maune Hiromi, Ikenaga Yuka, Yamamoto Isamu, Inaba Tadanobu, Azuma Junichi

Abstract excerpt

In this study, we established useful and reliable methods for the direct detection of the variants of CYP3A5 gene by polymerase chain reaction (PCR) and DdeI restriction analysis. The frequency of CYP3A5 related SNPs in 200 healthy Japanese male subjects was determined. The homozygous wild-type (*1/*1) frequency was 7.0% (14/200), the heterozygous (*1/*3) frequency was 32.5% (65/200) and the homozygous...

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PMID: 12042671
DOI: 10.1097/00008571-200206000-00009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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