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Article

CYP3A53 and CYP3A418 single nucleotide polymorphisms in a Chinese population.

Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2005

Hu Yong-Fang, He Jun, Chen Guo-Lin, Wang Dan, Liu Zhong-Qi, Zhang Che, Duan Li-Fang, Zhou Hong-Hao

Abstract excerpt

BACKGROUND: Human cytochrome P450 3A evolved to catalyze the metabolism of numerous common therapy drugs and endogenous molecules. Members of the CYP3A are the majority expressed in human liver and intestine, and there are marked interindividual differences in their protein expression and activity. The activity of CYP3A enzyme in Chinese is highly variable, exceeding 14-fold, and contributes greatly to variation...

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Identifiers

PMID: 15698606
DOI: 10.1016/j.cccn.2004.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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