Article
DNA repair gene XPD and susceptibility to arsenic-induced hyperkeratosis.
Toxicology letters - 20 Jul 2003
Ahsan Habibul, Chen Yu, Wang Qiao, Slavkovich Vesna, Graziano Joseph H, Santella Regina M
Abstract excerpt
Chronic exposure to inorganic arsenic is known to cause non-melanocytic skin and internal cancers in humans. An estimated 50-70 million people in Bangladesh have been chronically exposed to arsenic from drinking water and are at risk of skin and other cancers. We undertook the first study to examine whether genetic susceptibility, as determined by the codon 751 SNP (A-->C) of the DNA repair gene XPD, influences...
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