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Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in Bangladesh.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2007

Ahsan Habibul, Chen Yu, Kibriya Muhammad G, Slavkovich Vesna, Parvez Faruque, Jasmine Farzana, Gamble Mary V, Graziano Joseph H

Abstract excerpt

We conducted a case-control study to investigate interindividual variability in susceptibility to health effects of inorganic arsenic due to arsenic metabolism efficiency, genetic factors, and their interaction. A total of 594 cases of arsenic-induced skin lesions and 1,041 controls was selected from baseline participants in a large prospective cohort study in Bangladesh. Adjusted odds ratios (OR) for skin...

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PMID: 17548696
DOI: 10.1158/1055-9965.EPI-06-0676

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