Article
E-cadherin polymorphisms and susceptibility to arsenic-related skin lesions in West Bengal, India.
The Science of the total environment - 15 Mar 2012
Nriagu Jerome, Lin Tser-Sheng, Mazumder Debendranath Guha, Chatterjee Debashis
Abstract excerpt
OBJECTIVES: Although suppression of E-cadherin gene (CDH1) expression and exposure to arsenic have separately been associated with skin lesions, the combined effects of this "gene-environment" interaction have not been explored previously. STUDY DESIGN: A population-based cross-sectional survey. METHOD: This study involved 100 cases with skin lesions and 100 controls who were family members with no lesions. The...
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