Article
Susceptibility to arsenic-induced skin lesions from polymorphisms in base excision repair genes.
Carcinogenesis - 1 Jul 2007
Breton Carrie V, Zhou Wei, Kile Molly L, Houseman E A, Quamruzzaman Quazi, Rahman Mahmuder, Mahiuddin Golam, Christiani David C
Abstract excerpt
Genetic polymorphisms in the base excision DNA repair pathway may influence individual susceptibility to arsenic and the development of arsenic-induced skin lesions. Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 2001 to 2003 were analyzed using conditional logistic regression to assess the associations between four common base excision repair (BER) genetic...
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