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Association of single nucleotide polymorphism with arsenic-induced skin lesions and genetic damage in exposed population of West Bengal, India.

Mutation research. Genetic toxicology and environmental mutagenesis - 1 Oct 2016

Das Nandana, Giri Allan, Chakraborty Sayan, Bhattacharjee Pritha

Abstract excerpt

Long term consumption of arsenic contaminated water causes a number of dermatological and non-dermatological health problems and cancer. In a Genome Wide Association Study (GWAS) on Bangladesh population, a significant association of asingle nucleotide polymorphism (SNP) in the C10orf32 region (rs 9527; G>A) with urinary metabolites and arsenic induced skin lesions was reported. This study aims to evaluate the...

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PMID: 27692299
DOI: 10.1016/j.mrgentox.2016.09.006

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