Article
GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study.
Environmental health : a global access science source - 4 Dec 2007
Breton Carrie V, Kile Molly L, Catalano Paul J, Hoffman Elaine, Quamruzzaman Quazi, Rahman Mahmuder, Mahiuddin Golam, Christiani David C
Abstract excerpt
BACKGROUND: Chronic arsenic exposure is associated with an increased risk of skin, bladder and lung cancers. Generation of oxidative stress may contribute to arsenic carcinogenesis. METHODS: To investigate the association between arsenic exposure and oxidative stress, urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) was evaluated in a cohort of 97 women recruited from an arsenic-endemic region of Bangladesh in 2003....
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