Article
Precancerous and non-cancer disease endpoints of chronic arsenic exposure: the level of chromosomal damage and XRCC3 T241M polymorphism.
Mutation research - 10 Jan 2011
Kundu Manjari, Ghosh Pritha, Mitra Sanhita, Das J K, Sau T J, Banerjee Saptarshi, States J Christopher, Giri Ashok K
Abstract excerpt
Genetic variants are expected to play an important role in arsenic susceptibility. Our previous study revealed deficient DNA repair capacity to be a susceptibility factor for arsenicism. T241M polymorphism in XRCC3 (a homologous recombination repair pathway gene) is widely studied for its association with several cancers. We have investigated the association of XRCC3 T241M polymorphism with arsenic-induced...
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