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Article

Variation in the extent of microsatellite instability in human cell lines with defects in different mismatch repair genes.

Mutagenesis - 1 May 2003

Yamada N A, Castro A, Farber R A

Abstract excerpt

Mismatch repair deficiency results in the elevation of mutation rates in tumors, which is especially pronounced in simple repeat sequences (microsatellites). We have investigated the relationship between microsatellite mutagenesis and certain combinations of mutations in mismatch repair genes, using a frameshift reversion assay to determine the spontaneous mutation rates of a dinucleotide microsatellite in two...

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PMID: 12714694
DOI: 10.1093/mutage/18.3.277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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