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Article

Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A.

Mutation research - 3 Dec 1998

Kato T, Yatagai F, Glickman B W, Tachibana A, Ikenaga M

Abstract excerpt

The spectrum of mutations was determined at the hypoxanthine-guanine phosphoribosyltransferase (hprt) locus in the human uterine tumor cell line HEC-1-A which is defective in the mismatch repair gene hPMS2. The mutation frequency at the hprt locus in HEC-1-A was about two orders higher than that in wild type repair-proficient cells. The fifty-eight mutations detected were exclusively point mutations, with...

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Source

Identifiers

PMID: 9838164
DOI: 10.1016/s0027-5107(98)00208-5

Genes

PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A.PMID 9838164Read ↗

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