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Article

Multiplexed SNP genotyping using the Qbead system: a quantum dot-encoded microsphere-based assay.

Nucleic acids research - 15 Apr 2003

Xu Hongxia, Sha Michael Y, Wong Edith Y, Uphoff Janet, Xu Yanzhang, Treadway Joseph A, Truong Anh, O'Brien Eamonn, Asquith Steven, Stubbins Michael, Spurr Nigel K, Lai Eric H, Mahoney Walt

Abstract excerpt

We have developed a new method using the Qbead system for high-throughput genotyping of single nucleotide polymorphisms (SNPs). The Qbead system employs fluorescent Qdot semiconductor nanocrystals, also known as quantum dots, to encode microspheres that subsequently can be used as a platform for multiplexed assays. By combining mixtures of quantum dots with distinct emission wavelengths and intensities, unique...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12682378
DOI: 10.1093/nar/gng043
PMCID: PMC153755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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