Article
High-throughput SNP genotyping on universal bead arrays.
Mutation research - 3 Jun 2005
Shen Richard, Fan Jian-Bing, Campbell Derek, Chang Weihua, Chen Jing, Doucet Dennis, Yeakley Jo, Bibikova Marina, Wickham Garcia Eliza, McBride Celeste, Steemers Frank, Garcia Francisco, Kermani Bahram G, Gunderson Kevin, Oliphant Arnold
Abstract excerpt
We have developed a flexible, accurate and highly multiplexed SNP genotyping assay for high-throughput genetic analysis of large populations on a bead array platform. The novel genotyping system combines high assay conversion rate and data quality with >1500 multiplexing, and Array of Arrays formats. Genotyping assay oligos corresponding to specific SNP sequences are each linked to a unique sequence (address)...
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